Management impact of 18F-DCFPyL PET/CT in hormone-sensitive prostate cancer patients with biochemical recurrence after definitive treatment: a multicenter retrospective study.
Dennie MeijerPim J van LeeuwenPepijn M J OosterholtYves J L BodarHenk G van der PoelN Harry HendrikseMaarten L DonswijkMaurits WondergemAnnelies E VellekoopR Jeroen A van MoorselaarJakko A NieuwenhuijzenDaniela E Oprea-LagerAndré N VisPublished in: European journal of nuclear medicine and molecular imaging (2021)
In this study, we found a significant impact of 18F-DCFPyL PET/CT on the intended management of patients with biochemically recurrent hormone-sensitive prostate cancer. A positive 18F-DCFPyL PET/CT scan, positive pathological lymph node status, and a negative surgical margin status were significantly associated with increased odds of having a change of management based on 18F-DCFPyL PET/CT findings.