Activation of NLRP3 Inflammasome by Palmitic Acid in Human Sebocytes.
Yu-Ra JungJung-Min ShinChang-Hyeon KimSooil KimChang-Deok KimYoung Joon SeoJeung-Hoon LeeMyung ImYoung LeeYoung-Ho LeePublished in: Annals of dermatology (2021)
These findings indicate that PA activates the NLRP3 inflammasome before induction of an inflammatory response in sebocytes. Thus, PA may play a role in the inflammation of acne.