Application and research progress of magnetic resonance proton density fat fraction in metabolic dysfunction-associated steatotic liver disease: a comprehensive review.
Hongyan QiShanshan JiangJiang NanHang GuoCai ChengXin HeHongyang JinRongfan ZhangJunqiang LeiPublished in: Abdominal radiology (New York) (2024)
Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD), formerly known as Non-Alcoholic Fatty Liver Disease (NAFLD), is a chronic liver disorder associated with disturbances in lipid metabolism. The disease is prevalent worldwide, particularly closely linked with metabolic syndromes such as obesity and diabetes. Magnetic Resonance Proton Density Fat Fraction (MRI-PDFF), serving as a non-invasive and highly quantitative imaging assessment tool, holds promising applications in the diagnosis and research of MASLD. This paper aims to comprehensively review and summarize the applications and research progress of MRI-PDFF technology in MASLD, analyze its strengths and challenges, and anticipate its future developments in clinical practice.
Keyphrases
- magnetic resonance
- contrast enhanced
- type diabetes
- magnetic resonance imaging
- clinical practice
- adipose tissue
- high resolution
- oxidative stress
- fatty acid
- insulin resistance
- metabolic syndrome
- cardiovascular disease
- diffusion weighted imaging
- computed tomography
- weight gain
- skeletal muscle
- mass spectrometry
- current status
- liver fibrosis
- high fat diet induced
- body mass index
- photodynamic therapy