Catalytic System for Cross-Coupling of Heteroaryl Iodides with a Nitronyl Nitroxide Gold Derivative at Room Temperature.
Igor ZayakinGalina V RomanenkoIrina BagryanskayaBogdan UgrakMatvey V FedinEvgeny V TretyakovPublished in: Molecules (Basel, Switzerland) (2023)
A simple and highly effective methodology for the cross-coupling of heteroaryl iodides with NN-AuPPh 3 at room temperature is reported. The protocol is based on a novel catalytic system consisting of Pd 2 (dba) 3 ·CHCl 3 and the phosphine ligand Me CgPPh having an adamantane-like framework. The present protocol was found to be well compatible with various heteroaryl iodides, thus opening new horizons in directed synthesis of functionalized nitronyl nitroxides and high-spin molecules.