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Durvalumab Plus Carboplatin/Paclitaxel Followed by Maintenance Durvalumab With or Without Olaparib as First-Line Treatment for Advanced Endometrial Cancer: The Phase III DUO-E Trial.

Shannon Neville WestinKathleen MooreHye Sook ChonJung-Yun LeeJessica Thomes PepinMichael SundborgAyelet ShaiJoseph de la GarzaShin NishioMichael A GoldKe WangKristi McIntyreTodd D TillmannsStephanie V BlankJi-Hong LiuMichael McCollumFernando Contreras MejiaTadaaki NishikawaKathryn PenningtonZoltan NovakAndreia Cristina de MeloJalid SehouliDagmara Klasa-MazurkiewiczChristos PapadimitriouMarta Gil-MartinBirute BrasiunieneConor DonnellyPaula Michelle Del RosarioXiaochun LiuEls Van Nieuwenhuysennull null
Published in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Carboplatin/paclitaxel plus durvalumab followed by maintenance durvalumab with or without olaparib demonstrated a statistically significant and clinically meaningful PFS benefit in patients with advanced or recurrent endometrial cancer.
Keyphrases
  • endometrial cancer
  • phase iii
  • open label
  • clinical trial
  • phase ii
  • double blind
  • placebo controlled
  • randomized controlled trial
  • chemotherapy induced