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Harnessing the Power of CAR-NK Cells: A Promising Off-the-Shelf Therapeutic Strategy for CD38-Positive Malignancies.

Maryam AsadiRazie KianiVahid RazbanSeyed Nooreddin FarajiAmirhossein AhmadiJafar FallahiAmin RamezaniNasrollah Erfani
Published in: Iranian journal of immunology : IJI (2023)
The in vitro findings indicated that the anti-CD38 CAR-NK cells have the potential to be used as an off-the-shelf therapeutic strategy against CD38-positive malignancies. It is recommended that the present engineered NK cells undergo additional preclinical investigations before they can be considered for subsequent clinical trial studies.
Keyphrases
  • nk cells
  • clinical trial
  • big data
  • randomized controlled trial
  • open label
  • study protocol
  • cell therapy
  • bone marrow
  • double blind
  • phase iii
  • case control