Harnessing the Power of CAR-NK Cells: A Promising Off-the-Shelf Therapeutic Strategy for CD38-Positive Malignancies.
Maryam AsadiRazie KianiVahid RazbanSeyed Nooreddin FarajiAmirhossein AhmadiJafar FallahiAmin RamezaniNasrollah ErfaniPublished in: Iranian journal of immunology : IJI (2023)
The in vitro findings indicated that the anti-CD38 CAR-NK cells have the potential to be used as an off-the-shelf therapeutic strategy against CD38-positive malignancies. It is recommended that the present engineered NK cells undergo additional preclinical investigations before they can be considered for subsequent clinical trial studies.