DLBS3233 enhances nephrin and podocin expression also reduces oxidative stress marker and insulin receptor serine diabetic rats' podocytes.
Chandra I MohaniAchmad RudijantoAulanni'am Aulanni'amSetyawati SoehartoPublished in: Annals of medicine and surgery (2012) (2023)
DLBS3233 reduces oxidative stress by decreasing MDA and improves insulin resistance by increasing the expression of renal nephrin and podocin as well as decreasing insulin receptor serine.
Keyphrases
- diabetic rats
- oxidative stress
- type diabetes
- poor prognosis
- insulin resistance
- binding protein
- glycemic control
- dna damage
- ischemia reperfusion injury
- induced apoptosis
- protein kinase
- high fat diet
- breast cancer cells
- adipose tissue
- long non coding rna
- skeletal muscle
- endoplasmic reticulum stress
- signaling pathway
- high fat diet induced