A Nationwide Evaluation of Bevacizumab-based Treatments in Paediatric Low-Grade Glioma in the UK: Safety. Efficacy, Visual Morbidity and Outcomes.

Katherine GreenParaskevi PanagopoulouFelice D'ArcoPatricia O'HareRichard BowmanBronwen WaltersChristine DahlMette JorgensenPritesh PatelOlga SlaterRehana AhmedSimon BaileyFernando CarcellerRhiannon CollinsElizabeth CorleyMartin EnglishLisa HowellsAhmed KamalJohn-Paul KildayStephen LowisBlanche LumbErika PaceSusan PictonBarry PizerAyad ShafiqLena UzunovaHarriet WaymanShaun WilsonDarren HargraveEnrico Opocher

Published in: Neuro-oncology (2022)

BBTs provide effective short-term PLGG control and delay further progression, with a better sustained visual (best >worst eye) than radiological response. Further research could optimise the role of BBTs towards a potentially sight-saving strategy in OPG.

Keyphrases

low grade
high grade
cross sectional
intensive care unit
emergency department
metastatic colorectal cancer
type diabetes
adipose tissue
glycemic control