Gli promotes tumor progression through regulating epithelial-mesenchymal transition in non-small-cell lung cancer.

Long JiangJia HuangYingjie HuPeiji LuQingquan LuoLei Wang

Published in: Journal of cardiothoracic surgery (2020)

This study provides evidence for aberrant upregulation of the Gli signaling pathway and a strong association between expression of Gli versus AKT and EMT markers in NSCLC.

Keyphrases

epithelial mesenchymal transition
signaling pathway
poor prognosis
pi k akt
transforming growth factor
induced apoptosis
small cell lung cancer
cell proliferation
long non coding rna
binding protein
oxidative stress
brain metastases