Raptinal Induces Gasdermin E-Dependent Pyroptosis in Naïve and Therapy-Resistant Melanoma.

Megane Vernon Nicole A Wilski Daniel Kotas Weijia Cai Danielle Pomante Manoela Tiago Emad S Alnemri Andrew E Aplin

Published in: Molecular cancer research : MCR (2022)

Raptinal can rapidly induce pyroptosis in naïve and BRAFi plus MEKi-resistant melanoma, which may be beneficial for patients who have developed acquired resistance to targeted therapies.

Keyphrases

ejection fraction
newly diagnosed
nlrp inflammasome
stem cells
skin cancer
basal cell carcinoma
smoking cessation