Randomized Clinical Trial of Metoclopramide as Prophylaxis of Gastroesophageal Reflux Disease in Preterm Infants.

Adriana Del Pilar Montealegre-Pomar Nathalie Charpak

Published in: Paediatric drugs (2021)

Results show absence of effectiveness in the systematic use of metoclopramide as prophylaxis of GERD symptoms in premature infants. Additionally, no adverse effects attributable to the drug were found. ClinicalTrials.gov: NCT02907632; September 20, 2016. Retrospectively registered.

Keyphrases

gastroesophageal reflux disease
preterm infants
low birth weight
randomized controlled trial
systematic review
emergency department
double blind
drug induced
physical activity
adverse drug