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Site-discordant expression of myeloid cell nuclear differentiation antigen in blastic plasmacytoid dendritic cell neoplasm.

Philip L BulterysAtif SaleemRyanne A BrownRoberto A NovoaKerri E RiegerYasodha NatkunamSebastian Fernandez-Pol
Published in: American journal of clinical pathology (2024)
Our findings suggest that MNDA expression in BPDCN is anatomic site dependent and transient, with noncutaneous infiltrates showing more frequent expression than cutaneous infiltrates. These results caution against the use of MNDA to exclude BPDCN when considering the differential diagnosis of a blastic extramedullary infiltrate.
Keyphrases
  • dendritic cells
  • poor prognosis
  • immune response
  • binding protein
  • long non coding rna
  • bone marrow
  • cell therapy
  • high grade