Factors Influencing the Outcome of Patients with Primary Ewing Sarcoma of the Sacrum.
Victor RechlAndreas RanftVivek A BhadriBenedicte BrichardStéphane CollaudSona CyprovaHans EichTorben EkAndré B P van KuilenburgJendrik HardesLianne M HavemanWolfgang HartmannPéter HauserPhilip HeesenHeribert JürgensJukka KanervaThomas KuhneAnna RaciborskaJelena RasconArne StreitbürgerYasmin UhlenbruchBeate TimmermannJosephine KerstingMinh Thanh PhamUta DirksenPublished in: Sarcoma (2024)
Young age seems to positively influence patients` survival, especially in patients with primary metastatic disease. In this context, our results support other studies, stating that older age has a negative impact on survival. Tumor volume, metastases, and the type of local therapy modality have an impact on the outcome of sacral EwS. Level of evidence: Level 2. This trial is registered with NCT00020566 and NCT00987636.
Keyphrases
- end stage renal disease
- newly diagnosed
- chronic kidney disease
- ejection fraction
- squamous cell carcinoma
- small cell lung cancer
- peritoneal dialysis
- middle aged
- physical activity
- study protocol
- free survival
- randomized controlled trial
- phase iii
- patient reported outcomes
- mesenchymal stem cells
- bone marrow
- case control
- cell therapy
- replacement therapy