A retrospective review of gram-negative spinal infections in a single tertiary spinal centre over six years.
Daniel TadrossCieran McGroryJulia GreigRobert TownsendNeil ChivertonAdrian HighlandLee BreakwellAshley A ColePublished in: Bone & joint open (2024)
This is the largest published cohort of gram-negative spinal infections. In older patients with comorbidities and/or previous interventions in the last year, a high level of suspicion must be given to gram-negative infection with blood cultures and biopsy essential. Early organism identification permits targeted treatment and good initial clinical outcomes; however, mortality is 50% in this cohort at a mean of 4.2 years (2 to 6) after diagnosis.