Duration of dual antiplatelet therapy and stability of coronary heart disease: a 60 000-patient meta-analysis of randomised controlled trials.

Anda Bularga Mohammed Nooruddin MeahDimitrios DoudesisAnoop S V ShahNicholas L MillsDavid E NewbyKuan Ken Lee

Published in: Open heart (2021)

Our meta-analysis suggests that short (≤6 months) and shorter (≤3 months) durations DAPT are associated with lower risk of bleeding, equivalent efficacy and a trend towards lower all-cause mortality irrespective of coronary artery disease stability.

Keyphrases

antiplatelet therapy
systematic review
percutaneous coronary intervention
coronary artery disease
acute coronary syndrome
meta analyses
atrial fibrillation
type diabetes
randomized controlled trial
cardiovascular events
transcatheter aortic valve replacement