Lnc-IL7R alleviates PM 2.5 -mediated cellular senescence and apoptosis through EZH2 recruitment in chronic obstructive pulmonary disease.
Kang-Yun LeeShu-Chuan HoWei-Lun SunPo-Hao FengCheng-Wei LinKuan-Yuan ChenHsiao-Chi ChuangChien-Hua TsengTzu-Tao ChenSheng-Ming WuPublished in: Cell biology and toxicology (2022)
expression through EZH2 recruitment, and its dysfunction may augment cellular injury in COPD.
Keyphrases
- oxidative stress
- poor prognosis
- long non coding rna
- chronic obstructive pulmonary disease
- long noncoding rna
- air pollution
- particulate matter
- dna damage
- endoplasmic reticulum stress
- cell death
- endothelial cells
- lung function
- cell cycle arrest
- heavy metals
- polycyclic aromatic hydrocarbons
- binding protein
- stress induced
- mouse model
- cystic fibrosis
- cell proliferation