Four new tirucallane-type triterpenoids, polystanins H-K ( 1 - 4 ), were obtained from the stems and leaves of Aphanamixis polystachya . Their structures were elucidated by analysis of the spectroscopic data and comparison with literature data. Compounds 1 and 2 showed week inhibitory effects against NO production in LPS-stimulated RAW264.7 cells. All the isolates were investigated for their antifungal activities against drug-resistant Candida albicans .
Keyphrases
- candida albicans
- drug resistant
- multidrug resistant
- biofilm formation
- acinetobacter baumannii
- electronic health record
- induced apoptosis
- big data
- systematic review
- cell cycle arrest
- inflammatory response
- molecular docking
- high resolution
- anti inflammatory
- data analysis
- cell death
- clinical trial
- deep learning
- atomic force microscopy
- endoplasmic reticulum stress
- cell proliferation
- signaling pathway
- randomized controlled trial
- cystic fibrosis
- staphylococcus aureus
- escherichia coli
- study protocol