Electrostatic tweezer for droplet manipulation.
Yuankai JinWanghuai XuHuanhuan ZhangRuirui LiJing SunSiyan YangMinjie LiuHaiyang MaoZuankai WangPublished in: Proceedings of the National Academy of Sciences of the United States of America (2022)
Various physical tweezers for manipulating liquid droplets based on optical, electrical, magnetic, acoustic, or other external fields have emerged and revolutionized research and application in medical, biological, and environmental fields. Despite notable progress, the existing modalities for droplet control and manipulation are still limited by the extra responsive additives and relatively poor controllability in terms of droplet motion behaviors, such as distance, velocity, and direction. Herein, we report a versatile droplet electrostatic tweezer (DEST) for remotely and programmatically trapping or guiding the liquid droplets under diverse conditions, such as in open and closed spaces and on flat and tilted surfaces as well as in oil medium. DEST, leveraging on the coulomb attraction force resulting from its electrostatic induction to a droplet, could manipulate droplets of various compositions, volumes, and arrays on various substrates, offering a potential platform for a series of applications, such as high-throughput surface-enhanced Raman spectroscopy detection with single measuring time less than 20 s.
Keyphrases
- high throughput
- single cell
- raman spectroscopy
- ionic liquid
- molecular dynamics simulations
- healthcare
- physical activity
- high speed
- mental health
- minimally invasive
- high resolution
- single molecule
- mass spectrometry
- pseudomonas aeruginosa
- fatty acid
- biofilm formation
- drug delivery
- blood flow
- climate change
- sensitive detection
- quantum dots
- label free
- candida albicans
- tandem mass spectrometry
- solid phase extraction