A level-headed approach to measuring direct oral anticoagulants: A 2-year retrospective analysis of DOAC levels from a tertiary UK centre.

Nicholas D R DennyLynne KeighleyZubin SiganporiaJecko ThachilMichael J Nash

Published in: International journal of laboratory hematology (2018)

Our real-world study demonstrates that DOAC levels can be performed in a timely manner to influence clinical decision making. In addition, it suggests there is a wide variation in levels such that it can be difficult to predict in the real world. Overall, this supports the wider use of DOAC levels to help guide clinicians in managing patients taking these drugs.

Keyphrases

direct oral anticoagulants
venous thromboembolism
atrial fibrillation
end stage renal disease
newly diagnosed
cross sectional
palliative care
prognostic factors
peritoneal dialysis
patient reported