Combination of Indomethacin with Nanostructured Lipid Carriers for Effective Anticancer Therapy.
Vaikunthavasan ThiruchenthooranMarta EspinaMarta ŚwitalskaLorena Bonilla-VidalJoanna WietrzykMaria Luisa GarcíaEliana B SoutoElena Sánchez-LopezAnna GliszczyńskaPublished in: International journal of nanomedicine (2024)
We successfully developed IND-NLC for delivery of indomethacin to cancer cells and confirmed their antitumoral efficacy in in vitro studies. The results suggest that indomethacin encapsulated in lipid nanoparticles possesses high anticancer potential. Moreover, the presented strategy is highly promising and may offer a new alternative for future therapeutic drug innovations.