Expression of NLRP3 inflammasome in leprosy indicates immune evasion of Mycobacterium leprae.

Ana Luisa Gomes MendesHeloísa Di Matteo JoaquimMara Inês Stefanini ZamaeRamon Meira AssisJéssica Renata de Moura PeixotoMargarida Maria Gomes de AraújoAntônio Carlos Martins GuedesEdward José OliveiraVanessa Peruhype MagalhãesMarcelo Antônio Pascoal Xavier

Published in: Memorias do Instituto Oswaldo Cruz (2020)

Our results demonstrate that the NLRP3 inflammasome is inactive in leprosy, suggesting immune evasion of M. leprae.

Keyphrases

nlrp inflammasome
poor prognosis
mycobacterium tuberculosis