Fatty acid synthesis is indispensable for Kupffer cells to eliminate bacteria in ALD progression.
Liuyu XieBeng WuYuanyuan FanYe TaoXiaoyong JiangQing LiHuaiping ZhuHua WangChaojie HuPublished in: Hepatology communications (2024)
Our findings indicate the crucial role of de novo lipogenesis in maintaining effective KCs phagocytosis and suggest a therapeutic target for ALD based on fatty acid synthesis in KCs.