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Design and baseline characteristics of the AMPLITUDE-O cardiovascular outcomes trial of efpeglenatide, a weekly glucagon-like peptide-1 receptor agonist.

Ulagamadesan VenkatesanKelley BranchLaura HeenanStephano Del PratoNardev S KhurmiCarolyn S P LamRichard PratleyJulio RosenstockNaveed Sattar
Published in: Diabetes, obesity & metabolism (2020)
The results of the AMPLITUDE O trial will inform the use of exendin-based glucagon-like peptide-1 receptor agonist to people with T2DM and high CV risk, with and without CKD, in the presence and absence of an SGLT2 inhibitor.
Keyphrases
  • phase iii
  • study protocol
  • phase ii
  • clinical trial
  • chronic kidney disease
  • resting state
  • randomized controlled trial
  • open label
  • type diabetes
  • metabolic syndrome
  • adipose tissue
  • skeletal muscle
  • insulin resistance