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MNK inhibitor eFT508 (Tomivosertib) suppresses ectopic activity in human dorsal root ganglion neurons from dermatomes with radicular neuropathic pain.

Yan LiMegan L UhelskiRobert Y NorthJuliet M MwirigiClaudio E TatsuiJuan P CataGerman CorralesTheodore John PricePatrick M Dougherty
Published in: bioRxiv : the preprint server for biology (2023)
TJP is a co-founder of 4E Therapeutics, a company developing MNK inhibitors for neuropathic pain. The other authors declare no conflicts of interest.
Keyphrases
  • neuropathic pain
  • spinal cord
  • spinal cord injury
  • endothelial cells
  • induced pluripotent stem cells
  • signaling pathway
  • pluripotent stem cells
  • optical coherence tomography