TRIM3 facilitates estrogen signaling and modulates breast cancer cell progression.

Ting ZhuangBeibei WangXiaojing TanLe WuXin LiZhongbo LiYuqing CaiRongrong FanXiao YangChenmiao ZhangYan XiaZhiguo NiuBingtian LiuQi CaoYinlu DingZhipeng ZhouQingsong HuangHuijie Yang

Published in: Cell communication and signaling : CCS (2022)

Our study provides a novel posttranslational mechanism in estrogen signaling. Modulation of TRIM3 expression or function could be an interesting approach for breast cancer treatment. Video abstract.

Keyphrases

estrogen receptor
poor prognosis
single cell
cell therapy
stem cells
young adults
bone marrow
breast cancer risk