Multi-parametric MRI in the diagnosis and scoring of gastrointestinal acute graft-versus-host disease.
Francesca MaccioniUrsula La RoccaAlberto MilaneseLudovica BusatoArianna CleriMariangela LopezLucia ManganaroCarlo De FeliceCira Di GioiaAnna Rita VestriCarlo CatalanoAnna Paola IoriPublished in: European radiology (2023)
• We have developed a new promising MRI diagnostic score for GI-aGVHD with a sensitivity of 84.6% and specificity of 100%; results are to be confirmed by larger multicentric studies. • This MRI diagnostic score is based on the six MRI signs most frequently associated with GI-aGVHD: small-bowel inflammatory involvement, bowel wall stratification on T2-w images, wall stratification on post-contrast T1-w images, ascites, and edema of retroperitoneal fat and declivous soft tissues. • A broader MRI severity score based on 15 MRI signs showed no correlation with clinical staging but high prognostic value (100% sensitivity, 90% specificity for 1-month related mortality); these results also need to be confirmed by larger studies.
Keyphrases
- contrast enhanced
- magnetic resonance imaging
- diffusion weighted imaging
- magnetic resonance
- deep learning
- adipose tissue
- computed tomography
- small bowel
- convolutional neural network
- coronary artery disease
- type diabetes
- cardiovascular disease
- hepatitis b virus
- liver failure
- optical coherence tomography
- cardiovascular events
- fatty acid
- minimally invasive