MicroRNA-214-3p modified tetrahedral framework nucleic acids target survivin to induce tumour cell apoptosis.

Songhang LiYue SunTaoran TianXin QinShiyu LinTao ZhangQi ZhangMi ZhouXiaolin ZhangYi ZhouHu ZhaoBofeng ZhuXiaoxiao Cai

Published in: Cell proliferation (2019)

The unique expression of survivin in tumour cells and embryonic cells makes microRNA-tetrahedral framework nucleic acid a new targeted therapy. In addition, due to the functional diversity of microRNAs, this delivery system approach can be applied to a wide variety of fields, such as targeted therapy and tissue regeneration.

Keyphrases

induced apoptosis
nucleic acid
cell cycle arrest
stem cells
poor prognosis
cell proliferation
binding protein
wound healing