Carboxypeptidase B blocks ex vivo activation of the anaphylatoxin-neutrophil extracellular trap axis in neutrophils from COVID-19 patients.
Yue ZhangKai HanChunjing DuRui LiJingyuan LiuHui ZengLiuluan ZhuAng LiPublished in: Critical care (London, England) (2021)
Over-activation in anaphylatoxin-NET axis plays a pathological role in COVID-19. Early intervention in anaphylatoxins might help prevent thrombosis and disease progression in COVID-19 patients.