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Rolling the evolutionary dice: Neisseria commensals as proxies for elucidating the underpinnings of antibiotic resistance mechanisms and evolution in human pathogens.

Kelly M FrostSierra L Charron-SmithTerence C CotsonasDaniel C DimartinoRachel C EisenhartEric T EveringhamElle C HollandKainat ImtiazCory J KornowiczLydia E LenhardLiz H LynchNadia P MooreKavya PhadkeMakayla L ReedSamantha R SmithLiza L WardCrista B Wadsworth
Published in: Microbiology spectrum (2024)
selection to multiple antimicrobials and begin to define the number of paths to resistance. This study, and other similar works, may ultimately aid both surveillance efforts and clinical diagnostic development by nominating novel and conserved resistance mechanisms that may be at risk of rapid dissemination to pathogen populations.
Keyphrases
  • endothelial cells
  • public health
  • transcription factor
  • genome wide
  • gram negative
  • induced pluripotent stem cells
  • gene expression
  • pluripotent stem cells
  • dna methylation