The Gut Microbiome and Gastrointestinal Toxicities in Pelvic Radiation Therapy: A Clinical Review.

Byeongsang OhThomas EadeGillian LamourySusan CarrollMarita MorgiaAndrew KneeboneGeorge HrubyMark StevensFrances BoyleStephen ClarkeBrian CorlessMark P MolloyDavid RosenthalMichael Back

Published in: Cancers (2021)

Gut microbiome profiles are associated with GI toxicities and have the potential to predict RT/CRT-induced toxicities and quality of life (QoL) in patients undergoing those treatments. Further robust randomized controlled trials (RCTs) are required to elucidate the effect of gut microbiome profiles on RT-related adverse effects and responses to RT.

Keyphrases

radiation therapy
patients undergoing
randomized controlled trial
high glucose
diabetic rats
rectal cancer
heart failure
systematic review
oxidative stress
cardiac resynchronization therapy
risk assessment
left ventricular
climate change