Intracerebral administration of CTLA-4 and PD-1 immune checkpoint blocking monoclonal antibodies in patients with recurrent glioblastoma: a phase I clinical trial.

Johnny DuerinckJulia Katharina Schwarze Gil AwadaJens TijtgatFreya VaeyensCleo BertelsWietse GeensSamuel KleinLaura SeynaeveLouise CrasNicky D'HaeneAlex MichotteBen CaljonIsabelle SalmonMichaël BruneauMark KockxSonia Van DoorenAnne-Marie VanbinstHendrik EveraertRamses ForsythBart Neyns

Published in: Journal for immunotherapy of cancer (2022)

NCT03233152.

Keyphrases

clinical trial
phase ii
open label
double blind
study protocol
phase iii
randomized controlled trial