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Development and external validation of a risk prediction model for falls in patients with an indication for antihypertensive treatment: retrospective cohort study.

Lucinda ArcherConstantinos KoshiarisSarah Lay-FlurrieKym I E SnellRichard D RileyRichard StevensAmitava BanerjeeJuliet A Usher-SmithAndrew CleggRupert A PayneF D Richard HobbsRichard J McManusJames Peter Sheppardnull null
Published in: BMJ (Clinical research ed.) (2022)
This prediction model uses commonly recorded clinical characteristics and distinguishes well between patients at high and low risk of falls in the next 1-10 years. Although miscalibration was evident on external validation, the model still had potential clinical utility around risk thresholds of 10% and so could be useful in routine clinical practice to help identify those at high risk of falls who might benefit from closer monitoring or early intervention to prevent future falls. Further studies are needed to explore the appropriate thresholds that maximise the model's clinical utility and cost effectiveness.
Keyphrases
  • clinical practice
  • community dwelling
  • randomized controlled trial
  • blood pressure
  • current status
  • human health