Autologous stem cell transplantation in refractory Crohn's disease - low intensity therapy evaluation (ASTIClite): study protocols for a multicentre, randomised controlled trial and observational follow up study.

John A SnowdenChris HawkeyDaniel HindLizzie SwabyKatie MellorRichard EmsleyLaura MandefieldEllen LeeManuela BadoglioEmmanuelle PolgeMyriam LabopinJohn GribbenA Graham PockleyGemma A FouldsAlan LoboSimon TravisMiles ParkesJack SatsangiDiana PapaioannouJames O Lindsaynull nullnull null

Published in: BMC gastroenterology (2019)

The ASTIClite RCT was registered on 31st October 2017 ( ISRCTN17160440 ) and the EBMT follow-up study on 19th January 2018 ( ISRCTN31981313 ).

Keyphrases

stem cell transplantation
high dose
study protocol
cross sectional
clinical trial
bone marrow
cell therapy
low dose
mesenchymal stem cells