Lipid Nanoparticle-Based Inhibitors for SARS-CoV-2 Host Cell Infection.

Vinith YathindranathNura SafaMateusz Marek TomczykVernon DolinskyDonald W Miller

Published in: International journal of nanomedicine (2024)

Both LNP-Trap and LNP-Trim formulations were able to safely and effectively inhibit SARS-CoV-2 pseudoviral infection in airway epithelial cells. These studies provide proof-of-principle for a localized treatment approach for SARS-CoV-2 in the upper airway.

Keyphrases

sars cov
respiratory syndrome coronavirus
single cell
cell therapy
fatty acid
bone marrow