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Randomised clinical trial: Bifidobacterium lactis NCC2818 probiotic vs placebo, and impact on gut transit time, symptoms, and gut microbiology in chronic constipation.

Eirini DimidiAusra ZdanavicieneStephanos ChristodoulidesShiva TaheriPetra LouisPeter I DuncanNashmil EmamiRafael CrabbéC Antonio De CastroPeter McLeanGabriela E BergonzelliKevin WhelanS Mark Scott
Published in: Alimentary pharmacology & therapeutics (2018)
Bifidobacterium lactis NCC2818 was not effective in the management of mild chronic constipation. This study highlights the importance of further studies and their publication to better understand the strain-specific effects of probiotics.
Keyphrases
  • clinical trial
  • double blind
  • open label
  • irritable bowel syndrome
  • study protocol
  • phase iii
  • placebo controlled
  • phase ii
  • randomized controlled trial
  • case control
  • abdominal pain