Number of metastatic organs negatively affects the treatment sequence in patients with EGFR-TKI failure.
Takaaki MizunoHidehito HorinouchiSho WatanabeJun SatoRyo MoritaShuji MurakamiYasushi GotoShintaro KandaYutaka FujiwaraNoboru YamamotoYuichiro OhePublished in: Thoracic cancer (2020)
A relatively large number of metastatic organs and a poor PS were associated with the withholding of subsequent chemotherapy after failure of EGFR-TKI in EGFR-mutated NSCLC patients. Further research for patients with such a poor prognosis should be investigated in the future.
Keyphrases
- small cell lung cancer
- tyrosine kinase
- poor prognosis
- epidermal growth factor receptor
- advanced non small cell lung cancer
- long non coding rna
- end stage renal disease
- squamous cell carcinoma
- brain metastases
- ejection fraction
- newly diagnosed
- chronic kidney disease
- radiation therapy
- chronic myeloid leukemia
- atomic force microscopy
- current status
- mass spectrometry
- wild type