Mortality in patients with systemic lupus erythematosus: A meta-analysis of overall and cause-specific effects.
Young Ho LeeGwan Gyu SongPublished in: Lupus (2024)
This meta-analysis underscores a significant 2.87-fold elevation in the SMR among patients with SLE compared to the general population, transcending differences in sex or geographical regions. Moreover, an appreciable increase in mortality due to specific causes, including renal disease, infection, CVD, CVA, malignancy, and neuropsychiatric SLE, accentuates the imperative for targeted interventions to mitigate these elevated risks in SLE patients.
Keyphrases
- systemic lupus erythematosus
- systematic review
- disease activity
- end stage renal disease
- cardiovascular events
- ejection fraction
- newly diagnosed
- chronic kidney disease
- risk factors
- prognostic factors
- physical activity
- randomized controlled trial
- cancer therapy
- risk assessment
- meta analyses
- human health
- patient reported outcomes
- drug delivery