Potential of the dual mTOR kinase inhibitor AZD2014 to overcome paclitaxel resistance in anaplastic thyroid carcinoma.
Zorica MiloševićJasna BankovićJelena DinićChrisiida TsimplouliEvangelia SeretiMiodrag DragojVerica PaunovićZorka MilovanovićMarija StepanovićNikola TanićKostantinos DimasMilica PesicPublished in: Cellular oncology (Dordrecht) (2018)
Our data support results from recent phase I clinical trials using combinations of AZD2014 and PTX for the treatment of solid tumors. Such combinations may also be employed for the design of novel targeted ATC treatment strategies.