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Clonal expansion of CAR T cells harboring lentivector integration in the CBL gene following anti-CD22 CAR T-cell therapy.

Nirali N ShahHaiying QinBonnie YatesLing SuHaneen ShalabiMark RaffeldMark A AhlmanMaryalice Stetler-StevensonConstance M YuanShuang GuoSiyuan LiuStephen H HughesTerry J FryXiaolin Wu
Published in: Blood advances (2020)
Keyphrases
  • cell therapy
  • induced apoptosis
  • stem cells
  • mesenchymal stem cells
  • cell cycle arrest
  • genome wide
  • copy number
  • endoplasmic reticulum stress
  • signaling pathway
  • gene expression
  • oxidative stress