IL-1β Induces LDL Transcytosis by a Novel Pathway Involving LDLR and Rab27a.
Erika JangTse Wing Winnie HoJohn H BrumellFrançois LefebvreChangsen WangWarren L LeePublished in: Arteriosclerosis, thrombosis, and vascular biology (2024)
IL-1β induces LDL transcytosis by a distinct pathway requiring LDLR and Rab27a; this route differs from basal transcytosis. We speculate that induction of transcytosis by IL-1β may contribute to the acceleration of early disease.