Genomic analysis of transcriptional networks directing progression of cell states during MGE development.

Magnus SandbergLeila TaherJianxin HuBrian L BlackAlex S NordJohn L R Rubenstein

Published in: Neural development (2018)

Tcf12 expression in the SVZ of the MGE is mediated through aRE hs623. The activity of hs623 is dependent on LHX6, SOX and octamers. Thus, maintaining the expression of Tcf12 in the SVZ involves on TF pathways parallel and genetically downstream of NKX2-1.

Keyphrases

poor prognosis
transcription factor
gene expression
single cell
binding protein
long non coding rna
bone marrow