'Not at target': prevalence and consequences of inadequate disease control in systemic lupus erythematosus-a multinational observational cohort study.
Rangi Kandane-RathnayakeWorawit LouthrenooAlberta Y HoiShue-Fen LuoYeong-Jian J WuYi-Hsing ChenJiacai ChoAisha LateefLaniyati HamijoyoSandra V NavarraLeonid D ZamoraSargunan SockalingamYuan AnZhan-Guo LiYasuhiro KatsumataMasayoshi HarigaiYanjie HaoZhuoli ZhangJun KikuchiTsutomu TakeuchiB M D B BasnayakeMadelynn ChanKristine Pek Ling NgNicola TugnetSunil KumarShereen OonFiona GoldblattSean O'NeillKathryn A GibsonNaoaki OhkuboYoshiya TanakaSang-Cheol BaeWallace Chak Sing LauMandana NikpourVera GolderEric F Morandnull nullPublished in: Arthritis research & therapy (2022)
Failure to achieve LLDAS, high average disease activity, and episodes of HDAS were prevalent in SLE and were significantly associated with poor outcomes including organ damage, glucocorticoid exposure, poor quality of life, and mortality.