Sequential Treatment with Activin and Hepatocyte Growth Factor Induces FOXM1 to Promote Colorectal Cancer Liver Metastasis.

Hong Peng Ting Ye Lei Deng Xiaofang YangZheng JiangJinjun Guo

Published in: Canadian journal of gastroenterology & hepatology (2022)

Sequential treatment with activin and HGF accelerates CRC invasion and liver metastasis, which involves the upregulation and activation of FOXM1 and induction of CXCR4 and AFP.

Keyphrases

growth factor
cell proliferation
cell migration
poor prognosis
combination therapy