Analysis of Circulating Tumor DNA to Predict Risk of Recurrence in Patients With Esophageal and Gastric Cancers.
Brandon M HuffmanVasily N AushevGriffin L BuddeJoseph ChaoFarshid DayyaniDiana HannaGregory P BottaDaniel V T CatenacciSteven B MaronShifra KrinshpunShruti SharmaGiby V GeorgeMeenakshi MalhotraAdham JurdiSolomon MoshkevichAlexey AleshinPashtoon Murtaza KasiSamuel J KlempnerPublished in: JCO precision oncology (2022)
Using real-world data, we demonstrate that postoperative tumor-informed ctDNA detection in EGC is feasible and allows for enhanced patient risk stratification and prognostication during curative-intent therapy.
Keyphrases
- circulating tumor
- cell free
- circulating tumor cells
- case report
- patients undergoing
- electronic health record
- loop mediated isothermal amplification
- big data
- rectal cancer
- real time pcr
- free survival
- label free
- prognostic factors
- machine learning
- mesenchymal stem cells
- young adults
- bone marrow
- cell therapy
- deep learning
- single molecule
- childhood cancer