Samuel J Klempner (Samuel Klempner)

ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 62

Top Venues

JCO precision oncology

Nature medicine

Cancer discovery

The New England journal of medicine

Massachusetts General Hospital/Harvard Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Massachusetts General Hospital/Harvard Medical School Jun 4o 2019

United States

Assistant Professor :: Oncology

Publications

Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Anne Jenney, Caitlin E Mills, Emily J Robitschek, Thomas G R Davis, Sarah Kim, Amina Fu, Xiang Ma, Jia Gwee, Payal Tiwari, Peter P Du, Princy Sindurakar, Jun Tian, Arnav Mehta, Alexis M Schneider, Keren Yizhak, Moshe Sade-Feldman, Thomas LaSalle, Tatyana Sharova, Hongyan Xie, Shuming Liu, William A Michaud, Rodrigo Saad-Beretta, Kathleen B Yates, Arvin Iracheta-Vellve, Johan K E Spetz, Xingping Qin, Kristopher A Sarosiek, Gao Zhang, Jong Wook Kim, Mack Y Su, Angelina M Cicerchia, Martin Q Rasmussen, Samuel J Klempner, Dejan Juric, Sara I Pai, David M Miller, Anita Giobbie-Hurder, Jonathan H Chen, Karin Pelka, Dennie T Frederick, Susanna Stinson, Elena Ivanova, Amir R Aref, Cloud P Paweletz, David A Barbie, Debattama R Sen, David E Fisher, Ryan B Corcoran, Nir Hacohen, Peter K Sorger, Keith T Flaherty, Genevieve M Boland, Robert T Manguso, Russell William Jenkins
Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine 29 (2) (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine 29 (2) (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine (2023)
Sujin Hyung, Jihoon Ko, You Jeong Heo, Steven M Blum, Seung Tae Kim, Se Hoon Park, Joon Oh Park, Won Ki Kang, Ho Yeong Lim, Samuel J Klempner, Jeeyun Lee
Patient-derived exosomes facilitate therapeutic targeting of oncogenic MET in advanced gastric cancer. Science advances 9 (47) (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine 29 (2) (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine 29 (2) (2023)
Martin S Taylor, Connie Wu, Peter C Fridy, Stephanie J Zhang, Yasmeen Senussi, Justina Clarinda Wolters, Tatiana Cajuso, Wen-Chih Cheng, John D Heaps, Bryant D Miller, Kei Mori, Limor Cohen, Hua Jiang, Kelly R Molloy, Brian T Chait, Michael G Goggins, Irun Bhan, Joseph W Franses, Xiaoyu Yang, Mary-Ellen Taplin, Xinan Wang, David Chistopher Christiani, Bruce E Johnson, Matthew L Meyerson, Ravindra Uppaluri, Ann Marie Egloff, Elyssa N Denault, Laura M Spring, Tian-Li Wang, Ie-Ming Shih, Jennifer E Fairman, Euihye Jung, Kshitij S Arora, Osman H Yilmaz, Sonia Cohen, Tatyana Sharova, Gary Chi, Bryanna L Norden, Yuhui Song, Linda T Nieman, Leontios Pappas, Aparna Raj Parikh, Matthew R Strickland, Ryan B Corcoran, Tomas Mustelin, George Eng, Ömer H Yilmaz, Ursula A Matulonis, Steven J Skates, Bo R Rueda, Ronny Drapkin, Samuel J Klempner, Vikram Deshpande, David Tsai Ting, Michael P Rout, John LaCava, David R Walt, Kathleen H Burns
Ultrasensitive detection of circulating LINE-1 ORF1p as a specific multi-cancer biomarker. Cancer discovery (2023)
Harshabad Singh, Samuel J Klempner, Nelya Melnitchouk, Deepak P Chander, Ovidiu George Negrea, Anuj K Patel, Benjamin L Schlechter, Douglas A Rubinson, Brandon M Huffman, Chetan Nambiar, Joshua Remland, Elizabeth Andrews, Megan E Leahy, Lauren K Brais, Peter C Enzinger, Harvey J Mamon, Marios Giannakis, Jeffrey A Meyerhardt, Kimmie Ng, Kimberley J Perez, Andrew J Aguirre, Jeffrey W Clark, James M Cleary, Brian M Wolpin
Highly Sensitive Circulating Tumor DNA Assay Aids Clinical Management of Radiographically Occult Isolated Peritoneal Metastases in Patients With GI Cancer. JCO precision oncology 7 (2023)
Giovanni Randon, Yu Aoki, Romain Cohen, Leonardo Provenzano, Vincenzo Nasca, Samuel J Klempner, Steven B Maron, Riccardo Cerantola, Joseph Chao, Lorenzo Fornaro, Walter Ferrari Bravo, Filippo Ghelardi, Margherita Ambrosini, Paolo Manca, Massimiliano Salati, Akihito Kawazoe, Valerie Zhu, Darren Cowzer, Virginia Genovesi, Sara Lonardi, Kohei Shitara, Thierry André, Filippo Pietrantonio
Outcomes and a prognostic classifier in patients with microsatellite instability-high metastatic gastric cancer receiving PD-1 blockade. Journal for immunotherapy of cancer 11 (6) (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine (2023)
Pashtoon Murtaza Kasi, Leslie A Bucheit, Jiemin Liao, Jason S Starr, Pedro C Barata, Samuel J Klempner, David R Gandara, Ardaman Shergill, Luciana Madeira da Silva, Caroline Weipert, Nicole Zhang, Christopher Pretz, Aaron I Hardin, Lesli A Kiedrowski, Justin I Odegaard
Pan-Cancer Prevalence of Microsatellite Instability-High (MSI-H) Identified by Circulating Tumor DNA and Associated Real-World Clinical Outcomes. JCO precision oncology 7 (2023)
Jun Tian, Jonathan H Chen, Sherry X Chao, Karin Pelka, Marios Giannakis, Julian M Hess, Kelly P Burke, Vjola Jorgji, Princy Sindurakar, Jonathan Braverman, Arnav Mehta, Tomonori Oka, Mei Huang, David Lieb, Maxwell Spurrell, Jill N Allen, Thomas A Abrams, Jeffrey W Clark, Andrea C Enzinger, Peter C Enzinger, Samuel J Klempner, Nadine Jackson McCleary, Jeffrey A Meyerhardt, David P Ryan, Matthew B Yurgelun, Katie N Kanter, Emily E Van Seventer, Islam Baiev, Gary Chi, Joy Jarnagin, William B Bradford, Edmond Wong, Alexa G Michel, Isobel J Fetter, Giulia Siravegna, Angelo J Gemma, Arlene H Sharpe, Shadhmer Demehri, Rebecca Leary, Catarina D Campbell, Omer Yilmaz, Gad A Getz, Aparna Raj Parikh, Nir Hacohen, Ryan B Corcoran
Combined PD-1, BRAF and MEK inhibition in BRAF V600E colorectal cancer: a phase 2 trial. Nature medicine 29 (2) (2023)
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Anne Jenney, Caitlin E Mills, Emily J Robitschek, Thomas G R Davis, Sarah Kim, Amina Fu, Xiang Ma, Jia Gwee, Payal Tiwari, Peter P Du, Princy Sindurakar, Jun Tian, Arnav Mehta, Alexis M Schneider, Keren Yizhak, Moshe Sade-Feldman, Thomas LaSalle, Tatyana Sharova, Hongyan Xie, Shuming Liu, William A Michaud, Rodrigo Saad-Beretta, Kathleen B Yates, Arvin Iracheta-Vellve, Johan K E Spetz, Xingping Qin, Kristopher A Sarosiek, Gao Zhang, Jong Wook Kim, Mack Y Su, Angelina M Cicerchia, Martin Q Rasmussen, Samuel J Klempner, Dejan Juric, Sara I Pai, David M Miller, Anita Giobbie-Hurder, Jonathan H Chen, Karin Pelka, Dennie T Frederick, Susanna Stinson, Elena Ivanova, Amir R Aref, Cloud P Paweletz, David A Barbie, Debattama R Sen, David E Fisher, Ryan B Corcoran, Nir Hacohen, Peter K Sorger, Keith T Flaherty, Genevieve M Boland, Robert T Manguso, Russell William Jenkins
Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature 615 (7950) (2023)
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Anne Jenney, Caitlin E Mills, Emily J Robitschek, Thomas G R Davis, Sarah Kim, Amina Fu, Xiang Ma, Jia Gwee, Payal Tiwari, Peter P Du, Princy Sindurakar, Jun Tian, Arnav Mehta, Alexis M Schneider, Keren Yizhak, Moshe Sade-Feldman, Thomas LaSalle, Tatyana Sharova, Hongyan Xie, Shuming Liu, William A Michaud, Rodrigo Saad-Beretta, Kathleen B Yates, Arvin Iracheta-Vellve, Johan K E Spetz, Xingping Qin, Kristopher A Sarosiek, Gao Zhang, Jong Wook Kim, Mack Y Su, Angelina M Cicerchia, Martin Q Rasmussen, Samuel J Klempner, Dejan Juric, Sara I Pai, David M Miller, Anita Giobbie-Hurder, Jonathan H Chen, Karin Pelka, Dennie T Frederick, Susanna Stinson, Elena Ivanova, Amir R Aref, Cloud P Paweletz, David A Barbie, Debattama R Sen, David E Fisher, Ryan B Corcoran, Nir Hacohen, Peter K Sorger, Keith T Flaherty, Genevieve M Boland, Robert T Manguso, Russell William Jenkins
Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature 615 (7950) (2023)
Samuel J Klempner, Keun-Wook Lee, Kohei Shitara, Jean-Phillippe Metges, Sara Lonardi, David H Ilson, Nicola Fazio, Tae-Yong Kim, Li-Yuan Bai, Diarmuid Moran, Jianning Yang, Ahsan Arozullah, Jung Wook Park, Jeffrey J Raizer, Yung-Jue Bang, Manish A Shah
ILUSTRO: Phase 2 Multicohort Trial of Zolbetuximab in Patients with Advanced or Metastatic Claudin 18.2-Positive Gastric or Gastroesophageal Junction Adenocarcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Anne Jenney, Caitlin E Mills, Emily J Robitschek, Thomas G R Davis, Sarah Kim, Amina Fu, Xiang Ma, Jia Gwee, Payal Tiwari, Peter P Du, Princy Sindurakar, Jun Tian, Arnav Mehta, Alexis M Schneider, Keren Yizhak, Moshe Sade-Feldman, Thomas LaSalle, Tatyana Sharova, Hongyan Xie, Shuming Liu, William A Michaud, Rodrigo Saad-Beretta, Kathleen B Yates, Arvin Iracheta-Vellve, Johan K E Spetz, Xingping Qin, Kristopher A Sarosiek, Gao Zhang, Jong Wook Kim, Mack Y Su, Angelina M Cicerchia, Martin Q Rasmussen, Samuel J Klempner, Dejan Juric, Sara I Pai, David M Miller, Anita Giobbie-Hurder, Jonathan H Chen, Karin Pelka, Dennie T Frederick, Susanna Stinson, Elena Ivanova, Amir R Aref, Cloud P Paweletz, David A Barbie, Debattama R Sen, David E Fisher, Ryan B Corcoran, Nir Hacohen, Peter K Sorger, Keith T Flaherty, Genevieve M Boland, Robert T Manguso, Russell William Jenkins
Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature 615 (7950) (2023)
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Anne Jenney, Caitlin E Mills, Emily J Robitschek, Thomas G R Davis, Sarah Kim, Amina Fu, Xiang Ma, Jia Gwee, Payal Tiwari, Peter P Du, Princy Sindurakar, Jun Tian, Arnav Mehta, Alexis M Schneider, Keren Yizhak, Moshe Sade-Feldman, Thomas LaSalle, Tatyana Sharova, Hongyan Xie, Shuming Liu, William A Michaud, Rodrigo Saad-Beretta, Kathleen B Yates, Arvin Iracheta-Vellve, Johan K E Spetz, Xingping Qin, Kristopher A Sarosiek, Gao Zhang, Jong Wook Kim, Mack Y Su, Angelina M Cicerchia, Martin Q Rasmussen, Samuel J Klempner, Dejan Juric, Sara I Pai, David M Miller, Anita Giobbie-Hurder, Jonathan H Chen, Karin Pelka, Dennie T Frederick, Susanna Stinson, Elena Ivanova, Amir R Aref, Cloud P Paweletz, David A Barbie, Debattama R Sen, David E Fisher, Ryan B Corcoran, Nir Hacohen, Peter K Sorger, Keith T Flaherty, Genevieve M Boland, Robert T Manguso, Russell William Jenkins
Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature (2023)
Yi Sun, Or-Yam Revach, Seth Anderson, Emily A Kessler, Clara H Wolfe, Anne Jenney, Caitlin E Mills, Emily J Robitschek, Thomas G R Davis, Sarah Kim, Amina Fu, Xiang Ma, Jia Gwee, Payal Tiwari, Peter P Du, Princy Sindurakar, Jun Tian, Arnav Mehta, Alexis M Schneider, Keren Yizhak, Moshe Sade-Feldman, Thomas LaSalle, Tatyana Sharova, Hongyan Xie, Shuming Liu, William A Michaud, Rodrigo Saad-Beretta, Kathleen B Yates, Arvin Iracheta-Vellve, Johan K E Spetz, Xingping Qin, Kristopher A Sarosiek, Gao Zhang, Jong Wook Kim, Mack Y Su, Angelina M Cicerchia, Martin Q Rasmussen, Samuel J Klempner, Dejan Juric, Sara I Pai, David M Miller, Anita Giobbie-Hurder, Jonathan H Chen, Karin Pelka, Dennie T Frederick, Susanna Stinson, Elena Ivanova, Amir R Aref, Cloud P Paweletz, David A Barbie, Debattama R Sen, David E Fisher, Ryan B Corcoran, Nir Hacohen, Peter K Sorger, Keith T Flaherty, Genevieve M Boland, Robert T Manguso, Russell William Jenkins
Targeting TBK1 to overcome resistance to cancer immunotherapy. Nature (2023)
Parvathi A Myer, Jessica K Lee, Russell W Madison, Kith Pradhan, Justin Y Newberg, Carmen R Isasi, Samuel J Klempner, Garrett M Frampton, Jeffery S Ross, Jeffrey M Venstrom, Alexa B Schrock, Sudipto Das, Leonard Augenlicht, Amit Verma, John M Greally, Srilakshmi M Raj, Sanjay Goel, Siraj M Ali
The Genomics of Colorectal Cancer in Populations with African and European Ancestry. Cancer discovery 12 (5) (2022)
Steven B Maron, Stephanie Moya, Federica Morano, Matthew J Emmett, Joanne F Chou, Shalom Sabwa, Henry S Walch, Bryan Peterson, Alexa B Schrock, Liangliang Zhang, Yelena Y Janjigian, Sree Chalasani, Geoffrey Y Ku, Umut Disel, Peter Enzinger, Nataliya Uboha, Shumei Kato, Takayuki Yoshino, Kohei Shitara, Yoshiaki Nakamura, Anwaar Saeed, Pashtoon Murtaza Kasi, Joseph Chao, Jeeyun Lee, Marinela Capanu, Zev A Wainberg, Russell Petty, Filippo Pietrantonio, Samuel J Klempner, Daniel V T Catenacci
Epidermal Growth Factor Receptor Inhibition in Epidermal Growth Factor Receptor-Amplified Gastroesophageal Cancer: Retrospective Global Experience. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 40 (22) (2022)
Ryon P Graf, Virginia Fisher, James Creeden, Alexa B Schrock, Jeffery S Ross, Halla Nimeiri, Geoffrey R Oxnard, Samuel J Klempner
Real-world Validation of TMB and Microsatellite Instability as Predictive Biomarkers of Immune Checkpoint Inhibitor Effectiveness in Advanced Gastroesophageal Cancer. Cancer research communications 2 (9) (2022)
Rona Yaeger, Jared Weiss, Meredith S Pelster, Alexander I Spira, Minal Barve, Sai-Hong I Ou, Ticiana A Leal, Tanios S Bekaii-Saab, Cloud P Paweletz, Grace A Heavey, James G Christensen, Karen Velastegui, Thian Kheoh, Hirak Der-Torossian, Samuel J Klempner
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C. The New England journal of medicine (2022)
Brandon M Huffman, Vasily N Aushev, Griffin L Budde, Joseph Chao, Farshid Dayyani, Diana Hanna, Gregory P Botta, Daniel V T Catenacci, Steven B Maron, Shifra Krinshpun, Shruti Sharma, Giby V George, Meenakshi Malhotra, Adham Jurdi, Solomon Moshkevich, Alexey Aleshin, Pashtoon Murtaza Kasi, Samuel J Klempner
Analysis of Circulating Tumor DNA to Predict Risk of Recurrence in Patients With Esophageal and Gastric Cancers. JCO precision oncology 6 (2022)
Liangliang Zhang, Omar Hamdani, Ole V Gjoerup, Cheryl Cho-Phan, Jeremy Snider, Emily H Castellanos, Halla Nimeiri, Garrett M Frampton, Jeffrey M Venstrom, Geoffrey R Oxnard, Samuel J Klempner, Alexa B Schrock
ERBB2 Copy Number as a Quantitative Biomarker for Real-World Outcomes to Anti-Human Epidermal Growth Factor Receptor 2 Therapy in Advanced Gastroesophageal Adenocarcinoma. JCO precision oncology 6 (2022)
Margherita Ambrosini, Marzia Del Re, Francesco Pantano, Andrew E Hendifar, Alexander E Drilon, Guilherme Harada, Anne Hansen Ree, Samuel J Klempner, Gunhild Mari Mælandsmo, Norman John Carr, Hege G Russnes, James M Cleary, Harshabad Singh, Elisa Sottotetti, Antonia Martinetti, Giovanni Randon, Andrea Sartore-Bianchi, Iolanda Capone, Massimo Milione, Maria Di Bartolomeo, Filippo Pietrantonio
ALK Inhibitors in Patients With ALK Fusion-Positive GI Cancers: An International Data Set and a Molecular Case Series. JCO precision oncology 6 (2022)
Rona Yaeger, Jared Weiss, Meredith S Pelster, Alexander I Spira, Minal Barve, Sai-Hong I Ou, Ticiana A Leal, Tanios S Bekaii-Saab, Cloud P Paweletz, Grace A Heavey, James G Christensen, Karen Velastegui, Thian Kheoh, Hirak Der-Torossian, Samuel J Klempner
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C. The New England journal of medicine 388 (1) (2022)
Rona Yaeger, Jared Weiss, Meredith S Pelster, Alexander I Spira, Minal Barve, Sai-Hong I Ou, Ticiana A Leal, Tanios S Bekaii-Saab, Cloud P Paweletz, Grace A Heavey, James G Christensen, Karen Velastegui, Thian Kheoh, Hirak Der-Torossian, Samuel J Klempner
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C. The New England journal of medicine 388 (1) (2022)
Ryul Kim, Minae An, Hyuk Lee, Arnav Mehta, You Jeong Heo, Kyoung-Mee Kim, Song-Yi Lee, Jeonghyeon Moon, Seung Tae Kim, Byung-Hoon Min, Tae Jun Kim, Sun Young Rha, Won Ki Kang, Woong-Yang Park, Samuel J Klempner, Jeeyun Lee
Early Tumor-Immune Microenvironmental Remodeling and Response to First-Line Fluoropyrimidine and Platinum Chemotherapy in Advanced Gastric Cancer. Cancer discovery 12 (4) (2022)
Brandon M Huffman, Vasily N Aushev, Griffin L Budde, Joseph Chao, Farshid Dayyani, Diana Hanna, Gregory P Botta, Daniel V T Catenacci, Steven B Maron, Shifra Krinshpun, Shruti Sharma, Giby V George, Meenakshi Malhotra, Adham Jurdi, Solomon Moshkevich, Alexey Aleshin, Pashtoon Murtaza Kasi, Samuel J Klempner
Analysis of Circulating Tumor DNA to Predict Risk of Recurrence in Patients With Esophageal and Gastric Cancers. JCO precision oncology 6 (2022)
Brandon M Huffman, Vasily N Aushev, Griffin L Budde, Joseph Chao, Farshid Dayyani, Diana Hanna, Gregory P Botta, Daniel V T Catenacci, Steven B Maron, Shifra Krinshpun, Shruti Sharma, Giby V George, Meenakshi Malhotra, Adham Jurdi, Solomon Moshkevich, Alexey Aleshin, Pashtoon Murtaza Kasi, Samuel J Klempner
Analysis of Circulating Tumor DNA to Predict Risk of Recurrence in Patients With Esophageal and Gastric Cancers. JCO precision oncology 6 (2022)
Rona Yaeger, Jared Weiss, Meredith S Pelster, Alexander I Spira, Minal Barve, Sai-Hong I Ou, Ticiana A Leal, Tanios S Bekaii-Saab, Cloud P Paweletz, Grace A Heavey, James G Christensen, Karen Velastegui, Thian Kheoh, Hirak Der-Torossian, Samuel J Klempner
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C. The New England journal of medicine 388 (1) (2022)
Steven B Maron, Samuel J Klempner
Are You a TMBeliever? Mutations and Atezolizumab Response in Solid Tumors. Cancer discovery 12 (3) (2022)
Brandon M Huffman, Vasily N Aushev, Griffin L Budde, Joseph Chao, Farshid Dayyani, Diana Hanna, Gregory P Botta, Daniel V T Catenacci, Steven B Maron, Shifra Krinshpun, Shruti Sharma, Giby V George, Meenakshi Malhotra, Adham Jurdi, Solomon Moshkevich, Alexey Aleshin, Pashtoon Murtaza Kasi, Samuel J Klempner
Analysis of Circulating Tumor DNA to Predict Risk of Recurrence in Patients With Esophageal and Gastric Cancers. JCO precision oncology 6 (2022)
Brandon M Huffman, Vasily N Aushev, Griffin L Budde, Joseph Chao, Farshid Dayyani, Diana Hanna, Gregory P Botta, Daniel V T Catenacci, Steven B Maron, Shifra Krinshpun, Shruti Sharma, Giby V George, Meenakshi Malhotra, Adham Jurdi, Solomon Moshkevich, Alexey Aleshin, Pashtoon Murtaza Kasi, Samuel J Klempner
Analysis of Circulating Tumor DNA to Predict Risk of Recurrence in Patients With Esophageal and Gastric Cancers. JCO precision oncology 6 (2022)
Kyle D Staller, Yousef R Badran, David A Rosman, Samuel J Klempner, Richard Judelson
Case 31-2022: A 72-Year-Old Man with Heartburn, Nausea, and Inability to Eat. The New England journal of medicine 387 (15) (2022)
Rona Yaeger, Jared Weiss, Meredith S Pelster, Alexander I Spira, Minal Barve, Sai-Hong I Ou, Ticiana A Leal, Tanios S Bekaii-Saab, Cloud P Paweletz, Grace A Heavey, James G Christensen, Karen Velastegui, Thian Kheoh, Hirak Der-Torossian, Samuel J Klempner
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C. The New England journal of medicine 388 (1) (2022)
Sohee Kwon, Wenjie Ma, David A Drew, Samuel J Klempner, Brianna M Leonardo, Jacqueline J Flynn, Yin Cao, Edward L Giovannucci, Ying Bao, Charles S Fuchs, Mingyang Song, Andrew T Chan
Association Between Aspirin Use and Gastric Adenocarcinoma: A Prospective Cohort Study. Cancer prevention research (Philadelphia, Pa.) 15 (4) (2022)
Rona Yaeger, Jared Weiss, Meredith S Pelster, Alexander I Spira, Minal Barve, Sai-Hong I Ou, Ticiana A Leal, Tanios S Bekaii-Saab, Cloud P Paweletz, Grace A Heavey, James G Christensen, Karen Velastegui, Thian Kheoh, Hirak Der-Torossian, Samuel J Klempner
Adagrasib with or without Cetuximab in Colorectal Cancer with Mutated KRAS G12C. The New England journal of medicine 388 (1) (2022)
Jennifer Y Wo, Jeffrey W Clark, Christine E Eyler, Mari A Mino-Kenudson, Samuel J Klempner, Jill N Allen, Florence K Keane, Aparna R Parikh, Eric J Roeland, Lorraine C Drapek, David P Ryan, Ryan B Corcoran, Emily Van Seventer, Isobel J Fetter, Heather A Shahzade, Melin J Khandekar, Michael Lanuti, Christopher R Morse, Rebecca S Heist, Christine A Ulysse, Benjamin Christopher, Christian Baglini, Beow Y Yeap, John T Mullen, Theodore S Hong
Results and Molecular Correlates from a Pilot Study of Neoadjuvant Induction FOLFIRINOX Followed by Chemoradiation and Surgery for Gastroesophageal Adenocarcinomas. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (23) (2021)
Minsuk Kwon, Minae An, Samuel J Klempner, Hyuk Lee, Kyoung-Mee Kim, Jason K Sa, Hee Jin Cho, Jung Yong Hong, Yang Won Min, Tae Jun Kim, Woong-Yang Park, Won Ki Kang
Determinants of Response and Intrinsic Resistance to PD-1 Blockade in Microsatellite Instability-High Gastric Cancer. Cancer discovery 11 (9) (2021)
Katie N Kanter, Madeleine G Fish, Gianluca Mauri, Nora K Horick, Jill N Allen, Lawrence S Blaszkowsky, Jeffrey W Clark, David P Ryan, Ryan D Nipp, Bruce J Giantonio, Lipika Goyal, Jon Dubois, Janet E Murphy, Joseph W Franses, Samuel J Klempner, Eric J Roeland, Colin D Weekes, Jennifer Y Wo, Theodore S Hong, Emily E van Seventer, Ryan B Corcoran, Aparna Raj Parikh
Care Patterns and Overall Survival in Patients With Early-Onset Metastatic Colorectal Cancer. JCO oncology practice 17 (12) (2021)
Samuel J Klempner, Johanna C Bendell, Victoria Meucci Villaflor, Laura LaNiel Tenner, Stacey M Stein, James B Rottman, Girish S Naik, Cynthia A Sirard, Michael H Kagey, Marya F Chaney, John H Strickler
Safety, Efficacy, and Biomarker Results from a Phase Ib Study of the Anti-DKK1 Antibody DKN-01 in Combination with Pembrolizumab in Advanced Esophagogastric Cancers. Molecular cancer therapeutics 20 (11) (2021)
Jasmine Huynh, Kanishka Patel, Jun Gong, May Cho, Midhun Malla, Aparna Parikh, Samuel J Klempner
Immunotherapy in Gastroesophageal Cancers: Current Evidence and Ongoing Trials. Current treatment options in oncology 22 (11) (2021)
Arturo Loaiza-Bonilla, Al Bowen Benson, Axel Grothey, Misagh Karimi, Samuel J Klempner, Daniel Lin, Reshma L Mahtani, Heloisa P Soares
Use of Molecular Assays and Circulating Tumor DNA in Early-Stage Colorectal Cancer: A Roundtable Discussion of the Gastrointestinal Cancer Therapy Expert Group. The oncologist 26 (8) (2021)
David A Drew, Samuel J Klempner, Andrew T Chan
Metabolomics as a Tool for Biomarker Discovery in Gastric Cancer. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 30 (9) (2021)
Aparna R Parikh, Emily E Van Seventer, Giulia Siravegna, Anna V Hartwig, Ariel Jaimovich, Yupeng He, Katie N Kanter, Madeleine G Fish, Kathryn D Fosbenner, Benchun Miao, Susannah Phillips, John H Carmichael, Nihaarika Sharma, Joy Jarnagin, Islam Baiev, Yojan S Shah, Isobel J Fetter, Heather A Shahzade, Jill N Allen, Lawrence S Blaszkowsky, Jeffrey W Clark, Jon S Dubois, Joseph W Franses, Bruce J Giantonio, Lipika Goyal, Samuel J Klempner, Ryan D Nipp, Eric J Roeland, David P Ryan, Colin D Weekes, Jennifer Y Wo, Theodore S Hong, Liliana Bordeianou, Cristina R Ferrone, Motaz Qadan, Hiroko Kunitake, David Berger, Rocco Ricciardi, James C Cusack, Victoria M Raymond, AmirAli Talasaz, Genevieve Marie Boland, Ryan B Corcoran
Minimal Residual Disease Detection using a Plasma-only Circulating Tumor DNA Assay in Patients with Colorectal Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (20) (2021)
Noritaka Tanaka, Jessica J Lin, Chendi Li, Meagan B Ryan, Junbing Zhang, Lesli A Kiedrowski, Alexa G Michel, Mohammed U Syed, Katerina A Fella, Mustafa Sakhi, Islam Baiev, Dejan Juric, Justin F Gainor, Samuel J Klempner, Jochen K Lennerz, Giulia Siravegna, Liron Bar-Peled, Aaron N Hata, Rebecca S Heist, Ryan B Corcoran
Clinical Acquired Resistance to KRASG12C Inhibition through a Novel KRAS Switch-II Pocket Mutation and Polyclonal Alterations Converging on RAS-MAPK Reactivation. Cancer discovery 11 (8) (2021)
Adi Diab, Omid Hamid, John A Thompson, Willeke Ros, Ferry A L M Eskens, Toshihiko Doi, Siwen Hu-Lieskovan, Samuel J Klempner, Bishu Ganguly, Catherine Fleener, Xiao Wang, Tenshang Joh, Kai H Liao, Shahram Salek-Ardakani, Carrie Turich Taylor, Jeffrey Chou, Anthony B El-Khoueiry
A Phase I, Open-Label, Dose-Escalation Study of the OX40 Agonist Ivuxolimab in Patients with Locally Advanced or Metastatic Cancers. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Samuel J Klempner, Aaron N Hata
Can the Help Match the Hype? KRASG12C-Specific Inhibitors and Beyond. Cancer discovery 10 (1) (2020)
Jian Pan, Tiago C Silva, Nicole Gull, Qian Yang, Jasmine T Plummer, Stephanie Chen, Kenji Daigo, Takao Hamakubo, Sigal Gery, Ling-Wen Ding, Yan-Yi Jiang, Shaoyan Hu, Li-Yan Xu, En-Min Li, Yanbing Ding, Samuel J Klempner, Simon A Gayther, Benjamin P Berman, H Phillip Koeffler, De-Chen Lin
Lineage-Specific Epigenomic and Genomic Activation of Oncogene HNF4A Promotes Gastrointestinal Adenocarcinomas. Cancer research 80 (13) (2020)
Christie Y Jeon, Yu-Chen Lin, Samuel J Klempner, Bechien U Wu, Sungjin Kim, Kevin M Waters, Robert W Haile
Endoscopic History and Provider Characteristics Influence Gastric Cancer Survival in Asian Americans. Cancer prevention research (Philadelphia, Pa.) 13 (9) (2020)
Samuel J Klempner, Vivek Upadhyay, Joseph Chao
A Space-Time Continuum for Immunotherapy Biomarkers in Gastroesophageal Cancer? Clinical cancer research : an official journal of the American Association for Cancer Research 26 (24) (2020)
Samuel J Klempner, Russell Madison, Vivek Pujara, Jeffrey S Ross, Vincent A Miller, Siraj M Ali, Alexa B Schrock, Seung Tae Kim, Steven B Maron, Farshid Dayyani, Daniel V T Catenacci, Jeeyun Lee, Joseph Chao
FGFR2-Altered Gastroesophageal Adenocarcinomas Are an Uncommon Clinicopathologic Entity with a Distinct Genomic Landscape. The oncologist 24 (11) (2019)
Li Chen, Moli Huang, Jasmine Plummer, Jian Pan, Yan Yi Jiang, Qian Yang, Tiago Chedraoui Silva, Nicole Gull, Stephanie Chen, Ling Wen Ding, Omer An, Henry Yang, Yulan Cheng, Jonathan W Said, Ngan Doan, Winand Nm Dinjens, Kevin M Waters, Richard Tuli, Simon A Gayther, Samuel J Klempner, Benjamin P Berman, Stephen J Meltzer, De-Chen Lin, H Phillip Koeffler
Master transcription factors form interconnected circuitry and orchestrate transcriptional networks in oesophageal adenocarcinoma. Gut 69 (4) (2019)
Dan Zhao, Samuel J Klempner, Joseph Chao
Progress and challenges in HER2-positive gastroesophageal adenocarcinoma. Journal of hematology & oncology 12 (1) (2019)
Samuel J Klempner, Daniel V T Catenacci
Variety Is the Spice of Life, but Maybe Not in Gastroesophageal Adenocarcinomas. Cancer discovery 9 (2) (2019)
Samuel J Klempner, David Fabrizio, Shalmali Bane, Marcia Reinhart, Tim Peoples, Siraj M Ali, Ethan S Sokol, Garrett Frampton, Alexa B Schrock, Rachel Anhorn, Prasanth Reddy
Tumor Mutational Burden as a Predictive Biomarker for Response to Immune Checkpoint Inhibitors: A Review of Current Evidence. The oncologist 25 (1) (2019)
Samuel J Klempner, Steven B Maron, Leah Chase, Samantha Lomnicki, Zev A Wainberg, Daniel V T Catenacci
Initial Report of Second-Line FOLFIRI in Combination with Ramucirumab in Advanced Gastroesophageal Adenocarcinomas: A Multi-Institutional Retrospective Analysis. The oncologist 24 (4) (2018)
Phu Tran, Cham Nguyen, Samuel J Klempner
Targeting the Phosphatidylinositol-3-kinase Pathway in Gastric Cancer: Can Omics Improve Outcomes? International neurourology journal 20 (Suppl 2) (2016)

Samuel J Klempner.css-eqlu8i{font-size:small;padding-left:4px;} (Samuel Klempner)

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Samuel J Klempner (Samuel Klempner)