From ACTH-Dependent to ACTH-Independent Cushing's Syndrome from a Malignant Mixed Corticomedullary Adrenal Tumor: Potential Role of Embryonic Stem Cells.

Claudia Ramírez-RenteriaAna Laura Espinosa-De-Los-MonterosEspinosa-Cardenas EtualDaniel Marrero-RodríguezGuillermo CastellanosRocio Arreola-RosalesGuillermo Montoya-MartinezKeiko Taniguchi-PoncianoPaola Briseño-DíazMayte Lizeth Padilla-CristernaMaría Del Pilar Figueroa-CoronaMercado Moises

Published in: Case reports in endocrinology (2020)

The expression of cancer stem cell biomarkers points towards the involvement of primitive embryonic cells as the origin of this neoplasm and maybe to the clinically aggressive and biochemically changing behavior.

Keyphrases

embryonic stem cells
cancer stem cells
induced apoptosis
poor prognosis
cell cycle arrest
low grade
case report
oxidative stress
endoplasmic reticulum stress
binding protein
cell death
signaling pathway
climate change