An observational cohort study of pelvic floor photobiomodulation for treatment of chronic pelvic pain.
Neeraj KohliBarry JarnaginAngela R StoehrGeorgine LamvuPublished in: Journal of comparative effectiveness research (2021)
Aim: This research is the first to evaluate the effectiveness of trans-vaginal photobiomodulation therapy (TV-PBMT) for chronic pelvic pain. Materials & methods: Observational analysis of 128 women, undergoing TV-PBMT for chronic pelvic pain. Minimal clinically important difference, defined as ≥2-point drop on a 0-10 numeric pain rating scale (NPRS), and effect size Cohen d coefficient, was calculated over nine treatments for overall pain, and pain with activities. Results: Compared with baseline, 64.5% of women showed improvement in overall pain, pain with bowel movement, intercourse, exercise, urination, sitting and vulvar pain (minimal clinically important difference = -2.4, -2.0, -2.4, -2.1, -2.1, -2.0, -3.1; d = 0.9, 0.7, 0.9, 0.7, 0.7, 0.7, 0.9) by treatment 9. Conclusion: In this cohort, TV-PBMT resulted in improvement of pelvic pain without serious adverse events.
Keyphrases
- chronic pain
- pain management
- neuropathic pain
- rectal cancer
- randomized controlled trial
- stem cells
- early stage
- pregnant women
- mesenchymal stem cells
- magnetic resonance imaging
- spinal cord injury
- spinal cord
- physical activity
- polycystic ovary syndrome
- magnetic resonance
- wound healing
- drug induced
- pregnancy outcomes
- resistance training