Bone morphogenetic protein 2 inhibits growth differentiation factor 8-induced cell signaling via upregulation of gremlin2 expression in human granulosa-lutein cells.

Xiaoyan LuoHsun-Ming ChangYuyin YiYingpu SunPeter C K Leung

Published in: Reproductive biology and endocrinology : RB&E (2021)

Our findings provide new insight into the molecular mechanisms by which BMP2 modulates the cellular activity induced by GDF8 through the upregulated expression of their antagonist (GREM2).

Keyphrases

poor prognosis
endothelial cells
induced apoptosis
long non coding rna
high glucose
single cell
binding protein
mesenchymal stem cells
diabetic rats
cell proliferation
signaling pathway
stem cells
type diabetes
bone marrow
metabolic syndrome