The effect of increased frequency of hemodialysis on vitamin C concentrations: an ancillary study of the randomized Frequent Hemodialysis Network (FHN) daily trial.
Jochen G RaimannSamer R AbbasLi LiuBrett LariveGerald BeckPeter KotankoNathan W LevinGarry Handelmannull nullPublished in: BMC nephrology (2019)
Based on data from this large randomized-controlled trial no significant effect of the intervention on circulating plasma vitamin C concentrations was found, allaying the concerns that more frequent HD would affect the concentrations of water-soluble vitamins and adversely affect patient's well-being. Correlations between vitamin C and hemoglobin and PTH support the importance of vitamin C for normal bone and mineral metabolism, and anemia management.
Keyphrases
- randomized controlled trial
- water soluble
- study protocol
- chronic kidney disease
- phase iii
- end stage renal disease
- phase ii
- peritoneal dialysis
- open label
- clinical trial
- placebo controlled
- case report
- electronic health record
- bone mineral density
- machine learning
- big data
- systematic review
- postmenopausal women
- iron deficiency
- data analysis
- deep learning