Alterations of gut microbiome, metabolome and lipidome in Takayasu arteritis.
Luyun FanJunru ChenLili PanXiaohong XinBin GengLirui YangQian WangWenjun MaYing LouJin BianXiao CuiJing LiLu WangZhenzhen ChenWenjie WangChangting CuiShuangyue LiQiannan GaoQirui SongYue DengJiali FanJiachen YuHuimin ZhangYafeng LiJun CaiPublished in: Arthritis & rheumatology (Hoboken, N.J.) (2022)
This study firstly identifies the discriminatory gut microbes in TA. Dysbiotic microbes also link to TA phenotypes directly or indirectly via metabolic and lipid modules. Further explorations on microbiome-metagenome interface in TA subtype prediction and pathogenesis are indicated.